Abacavir Mylan 300 mg Film-coated Tablets Uses & Price

Did you know Abacavir Mylan 300 mg Film-coated Tablets can cost just ₹5.43 per tablet? This is 88% cheaper than Albavir Tablet, which costs ₹46.57 per tablet. This big price gap shows how important it is to know the cost of HIV treatments.

Abacavir Mylan 300 mg Film-coated Tablets are key for treating HIV. They are made by Mylan Laboratories. You can find them in the United States, Nepal, Australia, Canada, and Singapore. This makes them a more affordable choice for people with HIV.

Key Takeaways

• Abacavir Mylan 300 mg Film-coated Tablets are a cost-effective HIV treatment option, priced at 88% less than the popular Albavir Tablet.
• The medication is a nucleoside reverse transcriptase inhibitor (NRTI) used in combination with other antiretroviral agents to treat HIV-1 infection.
• Abacavir Mylan is available in several countries, including the United States, Nepal, Australia, Canada, and Singapore.
• Understanding the pricing and availability of different HIV treatment options can help patients and healthcare providers make informed decisions.
• The significant price difference between Abacavir Mylan and Albavir Tablet highlights the need for affordable and accessible HIV medications.

Understanding Abacavir Mylan

Abacavir Mylan is key in fighting HIV-1. It’s a man-made drug that stops the virus from copying itself. By using it with other medicines, it keeps the virus from growing in the body.

What is Abacavir?

Abacavir is the main part of Abacavir Mylan 300 mg tablets. It’s a type of drug that stops the virus from making copies. This is because it blocks the virus’s way to make more copies.

Mechanism of Action

When taken, abacavir turns into a form that stops the virus. It does this by getting in the way of the virus’s DNA. This stops the virus from making more copies.

Drug Classification

Abacavir Mylan is a type of HIV-1 drug. It comes in a tablet with 300 mg of abacavir and 300 mg of lamivudine. This combo is for treating HIV-1 in adults and kids.

Medication	Strength	Approved Dose	Dosage Form
Abacavir Mylan	300 mg abacavir 300 mg lamivudine	1 tablet once daily	Film-coated tablet

Abacavir Mylan is a big help for those with HIV-1. It keeps the virus from making more copies. This helps people stay healthy while on treatment.

Therapeutic Applications and Indications

Abacavir Mylan 300 mg Film-coated Tablets treat HIV-1 infection in adults and kids over 3 months. They should be used with other HIV drugs. This is because using them alone can lead to drug resistance.

The uses of Abacavir Mylan 300 mg Film-coated Tablets include:

• Treatment of HIV-1 infection in combination with other antiretroviral drugs
• Incorporation into combination antiretroviral therapy regimens for the management of HIV-1 infection
• Use in both adult and pediatric populations (3 months and older) infected with HIV-1

The data shows that 83% of abacavir is absorbed by the body. After taking 300 mg twice a day, the highest level of abacavir in the blood is 3.0 ± 0.89 mcg per mL. Taking 600 mg once gives a peak of 4.26 ± 1.19 mcg per mL.

Pharmacokinetic Parameter	Value
Geometric Mean Absolute Bioavailability of Abacavir Tablets	83%
Steady-State Peak Serum Abacavir Concentration (Cmax) after 300 mg Twice Daily	3.0 ± 0.89 mcg/mL
Cmax after Single Dose of 600 mg	4.26 ± 1.19 mcg/mL

Abacavir Mylan 300 mg Film-coated Tablets are key in combination antiretroviral therapy for HIV-1 treatment. They offer a solid choice for doctors and patients.

Abacavir Mylan 300 mg Film-coated Tablets USES SIDE EFFECTS PRICE

Abacavir Mylan 300 mg film-coated tablets are key in fighting HIV. They help slow down the virus, cutting down on health problems. This improves a person’s health and life span.

Standard Dosage Guidelines

Adults should take 300 mg of abacavir twice a day or 600 mg once a day. Kids get a dose based on their weight. It’s crucial to stick to the right dose for best results and safety.

Cost Considerations

The cost of Abacavir Mylan 300 mg tablets varies by location and insurance. On average, it’s about $46.57 per tablet. Prices can change due to discounts, insurance, and market conditions.

Insurance Coverage

Many insurances cover Abacavir Mylan 300 mg tablets. It’s seen as a cost-effective HIV treatment. Patients should talk to their insurance to know what’s covered and what they might pay out of pocket.

Knowing about dosage, cost, and insurance helps those with HIV make smart choices. It ensures they get the medication they need.

“Abacavir Mylan 300 mg film-coated tablets have been a game-changer in my HIV management. The affordable price and comprehensive insurance coverage have made this medication a cost-effective therapy for me.”

Important Safety Warnings

When taking Abacavir Mylan 300 mg Film-coated Tablets, it’s key to know some safety tips. Serious hypersensitivity reactions can happen. These reactions can be deadly.

Before starting, patients need to be tested for the HLA-B*5701 allele. This test helps find out if they might have a bad reaction.

Lactic acidosis and hepatomegaly with steatosis are also risks. These can be very serious and even fatal. Also, people with HIV-1 and hepatitis B virus (HBV) might face severe hepatitis B flare-ups if they stop taking lamivudine.

Key Safety Concerns	Statistics
Hypersensitivity Reactions	About 5% of people taking abacavir get a hypersensitivity reaction. Those with the HLA-B*5701 allele face a much higher risk (48% to 61%).
Lactic Acidosis and Hepatomegaly	Lactic acidosis and severe liver problems, including death, have been linked to nucleoside analogues.
Hepatitis B Exacerbations	Severe hepatitis B flare-ups have been seen in those with HIV-1 and HBV who stop taking lamivudine.

Healthcare providers and patients must know these safety warnings. This ensures Abacavir Mylan 300 mg Film-coated Tablets are used safely and effectively.

Hypersensitivity Reactions and Management

Abacavir is a key part of Abacavir Mylan. It can cause hypersensitivity reactions (HSR), which are very serious. These reactions include fever, rash, and stomach problems. People with the HLA-B*5701 gene are at higher risk.

Risk Factors

The main risk is having the HLA-B*5701 allele. It’s important to test for this gene before starting abacavir. This helps avoid serious reactions.

Monitoring Protocol

• Watch for signs of hypersensitivity, especially in the first six weeks.
• Check vital signs, skin, and breathing often.
• Stop abacavir right away if hypersensitivity is suspected.

Emergency Response

If hypersensitivity is thought to be happening, stop abacavir for good. Starting it again can be very dangerous. Quick medical help is needed, and care should be given as needed.

Abacavir Hypersensitivity Incidence	Pediatric HIV-1 Studies	Adult HIV-1 Studies
Fever and/or Chills	≥5%	–
Nausea and Vomiting	≥5%	–
Skin Rashes	≥5%	–
Overall Incidence	–	>5%

It’s crucial to watch closely, act fast, and stop abacavir for abacavir hypersensitivity. Testing for the HLA-B*5701 gene before starting helps keep patients safe.

Drug Interactions and Contraindications

Abacavir Mylan 300 mg film-coated tablets can interact with many drugs. There are also certain things you should not take with it. Doctors need to know these to keep patients safe.

Potential Drug Interactions

Abacavir may not work as well with ethanol. Also, some people might need more methadone when taking Abacavir Mylan.

Contraindications

Abacavir Mylan 300 mg film-coated tablets should not be taken by:

• People who have had hypersensitivity to abacavir or any part of the product
• Those with moderate or severe liver problems

Be careful when taking Abacavir Mylan with other drugs that can harm the kidneys.

Interaction	Potential Impact
Ethanol	Decreased elimination of abacavir
Methadone	Increased dosage may be required in some patients
Hypersensitivity to abacavir or product components	Contraindicated
Moderate or severe hepatic impairment	Contraindicated
Drugs affecting renal function	Use caution when co-administering

The complex profile of drug interactions and contraindications with Abacavir Mylan 300 mg film-coated tablets shows the need for careful patient evaluation and monitoring. This ensures the safe and effective use of this medication.

Administration Guidelines

Abacavir Mylan 300 mg Film-coated Tablets can be taken with or without food. Keep the medicine at room temperature. Make sure it’s away from moisture, heat, and light. Always keep the bottle tightly closed.

Proper Storage

Store Abacavir Mylan 300 mg Film-coated Tablets at room temperature. This means between 15°C to 30°C (59°F to 86°F). Keep it away from sunlight, heat, and moisture to keep it working well.

Handling Instructions

• Read the Medication Guide with each prescription and refill.
• Carry a warning card always because of the risk of hypersensitivity reactions.
• Call your healthcare provider right away if you see signs of a hypersensitivity reaction. This includes fever, rash, nausea, vomiting, or fatigue.

Following the right storage and handling is key for safe use of Abacavir Mylan 300 mg Film-coated Tablets. Teach patients these steps to get the best results and avoid bad side effects.

Medication	Dosage	Storage Instructions
Abacavir Mylan 300 mg Film-coated Tablets	600 mg daily, administered as 300 mg twice daily or 600 mg once daily	Store at room temperature, between 15°C to 30°C (59°F to 86°F), away from moisture, heat, and light

“Proper storage and handling of Abacavir Mylan 300 mg Film-coated Tablets are essential to ensure the medication’s effectiveness and safety.”

Special Patient Populations

Abacavir Mylan is safe for kids as young as 3 months old. The dose is based on the child’s weight. But, there’s not much data on using it in people over 65.

For those with mild liver problems, no dose change is needed. But, it’s not safe for those with more serious liver issues. Also, no dose change is needed for people with kidney problems.

When giving Abacavir Mylan to young patients or seniors, extra care is needed. Doctors should weigh the benefits and risks for each patient. This is especially true for those with liver or kidney issues.

FAQ

What is Abacavir Mylan 300 mg Film-coated Tablets?

Abacavir Mylan 300 mg Film-coated Tablets treat HIV-1 infection. They are used with other medicines. This drug is an NRTI that lowers HIV in the blood.

How does Abacavir work?

Abacavir stops HIV-1 reverse transcriptase. It turns into carbovir triphosphate in the body. This stops viral DNA from growing.

What are the recommended dosages for Abacavir Mylan 300 mg Film-coated Tablets?

Adults should take 300 mg twice a day or 600 mg once a day. Kids’ doses depend on their weight.

What are the common side effects of Abacavir Mylan 300 mg Film-coated Tablets?

Side effects include nausea, headache, and diarrhea. Serious issues like hypersensitivity reactions and liver problems can also happen.

How much do Abacavir Mylan 300 mg Film-coated Tablets cost?

Prices vary by location and insurance. Check with your insurance for details.

What are the important safety warnings for Abacavir Mylan 300 mg Film-coated Tablets?

Serious reactions, including death, can happen. Screen for HLA-B*5701 allele before starting. Lactic acidosis and liver problems are also risks.

How can hypersensitivity reactions to Abacavir be managed?

Hypersensitivity is a serious reaction. It’s more common in those with HLA-B*5701 allele. Stop the drug if a reaction starts and never use it again.

What are the contraindications and drug interactions for Abacavir Mylan 300 mg Film-coated Tablets?

Don’t use if you’re allergic or have liver problems. It can interact with alcohol and methadone. Be careful with other drugs that affect the kidneys.

How should Abacavir Mylan 300 mg Film-coated Tablets be stored and handled?

Take with or without food. Store at room temperature, away from moisture and light. Keep the bottle closed. Always carry a warning card.

Can Abacavir Mylan 300 mg Film-coated Tablets be used in special patient populations?

It’s okay for kids 3 months and older, based on weight. Limited data for older adults. It’s safe for most with kidney or liver issues.